امروز : یکشنبه   ۰۲. مهر ۱۳۹۶   /    3. محرم 1439   /    24. سپتامبر 2017

Comparison of abdominoperinea l resection and low anterior resection in lower and middle rectal cancer

Abstract
Introduction: This study aimed to investigate local control and survival rates following abdominoperineal resection (APR) compared with low anterior resection (LAR) in lower and middle rectal cancer.
Methods: In this retrospective study , 153 patients with newly histologically proven rectal adenocar-cinoma located at low and middle third that were treated between 2004 and 2010 at a tertiary hos-
pital. The tumors were pathologically staged according to the 7th edition of the American Joint Committee on Cancer (AJCC) staging system. Surgery was applied for 138 (90%) of the patients,of which 96 (70%) underwent LAR and 42 were (30%) treated with APR. Total mesorectal excision was performed for all patients. In addition, 125 patients (82%) received concurrent (neoadjuvant,adjuvant or palliative) pelvic chemoradiation, and 134 patients (88%) received neoadjuvant, adju-vant or concurrent chemotherapy. Patients’ follow-up ranged from 4 to 156 (median 37) months.

Results: Of 153 patients, 89 were men and 64 were women with a median age of 57 years.


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